- Edited
I generally ignore toxic comments, but I always answer to toxic reviews because there's often behind them a slandering intent and the content of the arguments is generally some non sense with very few chapters read. A logical and calm answer to them can do wonders and sometimes they have valid points.
You generally know if they're toxic readers when they answer you back. Many don't. If they do, the tone tells you instantly if it's possible to talk with them in an intelligent way.
Anyway, except for a few authors here, most webnovels are first drafts, mine included. So taking notice of every feedack, positive or negative is very important. When there's enough, it gives you a clear idea of what you need to improve or rewrite.